Clinical features and management of iris melanoma - a systematic review

Introduction and purpose Uveal melanoma is the most common primary intraocular malignancy in adults. Most of them arise choroid ciliary body, whereas 2-5 % cases are located to iris. Nevertheless, during last few decades incidence this neoplasm has been increasing. The aim study discuss risk factors, clinical features methods diagnosis treatment iris melanoma. Description state knowledge Iris melanomas vary their shape, size, degree pigmentation behavior commonly present as a nodular tumor lower temporal quadrant. This localisation linked exposure solar radiation, which among light-colored iris, skin color pre- existing naevus, factor for malignancy. Gender predilection development unclear, however, some studies indicate predominance female patients. symptoms growth pre-existing detection new, dark lesion, pain secondary elevated IOP blurred vision. Due anterior location site uvea, early possible. Slit-lamp examination, gonioscopy, ultrasound biomicroscopy (UBM) allow staging guide appropriate treatment. As many lesions have benign prognosis, surgical resection or radiotherapy efficient way allows good local control. Summary least frequent all uveal usually presents variably pigmented, elevated, solitary lesion. When there suspicion slit- lamp examination UBM should be performed. diagnosed it can successfully treated.